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Result Content Idea Research
1 High-Throughput Protein Engineering Improves the Antigenicity and Stability of Soluble HIV-1 Envelope Glycoprotein SOSIP Trimers
2 Researchers uncover clues about how HIV virus mutates: Study findings could inform smarter HIV vaccine design
3 Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread
4 New library of HIV mutants could inform vaccine design
5 Improving the Expression and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers by Targeted Sequence Changes
6 Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors
7 Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates
8 Cell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 Envelope
9 HIV-1 gp41 Residues Modulate CD4-Induced Conformational Changes in the Envelope Glycoprotein and Evolution of a Relaxed Conformation of gp120
10 Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro
11 New TSRI study shows HIV structure in unprecedented detail
12 HIV-1 Subtype C-Infected Children with Exceptional Neutralization Breadth Exhibit Polyclonal Responses Targeting Known Epitopes
13 Functional Stability of HIV-1 Envelope Trimer Affects Accessibility to Broadly Neutralizing Antibodies at Its Apex
14 HIV-1 vaccine design through minimizing envelope metastability
15 A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer Stability
16 Comparison of Uncleaved and Mature Human Immunodeficiency Virus Membrane Envelope Glycoprotein Trimers
17 Identification of Novel Structural Determinants in MW965 Env That Regulate the Neutralization Phenotype and Conformational Masking Potential of Primary HIV-1 Isolates
18 Glycosylation Benchmark Profile for HIV-1 Envelope Glycoprotein Production Based on Eleven Env Trimers
19 Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers
20 Conformational States of a Soluble, Uncleaved HIV-1 Envelope Trimer
21 Molecular Basis of Unusually High Neutralization Resistance in Tier 3 HIV-1 Strain 253-11
22 Dense Array of Spikes on HIV-1 Virion Particles
23 Functional Optimization of Broadly Neutralizing HIV-1 Antibody 10E8 by Promotion of Membrane Interactions
24 HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual
25 Multiple Antibody Lineages in One Donor Target the Glycan-V3 Supersite of the HIV-1 Envelope Glycoprotein and Display a Preference for Quaternary Binding
26 Clonify: unseeded antibody lineage assignment from next-generation sequencing data
27 Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity
28 Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization
29 Genetically Intact but Functionally Impaired HIV-1 Env Glycoproteins in the T-Cell Reservoir
30 Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research